• Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study 

      Reiseter, Silje; Molberg, Øyvind; Gunnarsson, Ragnar; Lund, May Brit; Aaløkken, Trond Mogens; Aukrust, Pål; Ueland, Thor; Garen, Torhild; Brunborg, Cathrine; Michelsen, Annika; Abraityte, Aurelija; Hoffmann-Vold, Anna-Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-28)
      Introduction: Systemic sclerosis (SSc) and mixed connective tissue disease (MCTD) are chronic immune-mediated disorders complicated by vascular organ damage. The aim of this study was to examine the serum levels of the markers of neoangiogenesis: endostatin and vascular endothelial growth factor (VEGF), in our unselected cohorts of SSc and MCTD. Methods: Sera of SSc patients (N = 298) and MCTD ...
    • Pulmonary manifestations and progression of lung disease in juvenile-onset mixed connective tissue disease 

      Hetlevik, Siri Opsahl; Flatø, Berit; Aaløkken, Trond Mogens; Samersaw-Lund, May Brit; Reiseter, Silje; Mynarek, Georg; Nordal, Ellen Berit; Rygg, Marite; Lilleby, Vibke (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-01)
      <i>Objective</i> - To assess the occurrence and extent of interstitial lung disease (ILD) in patients with juvenile mixed connective tissue disease (JMCTD), compare pulmonary function in patients and matched controls, study associations between ILD and disease-related variables, and examine progression of pulmonary manifestations over time.<p> <p><i>Methods</i> - A cohort of 52 patients with JMCTD ...